Time-varying residential neighborhood effects on cardiometabolic health - MET’HOOD


The MET’HOOD project investigates the relationships between the socio-economic and physical environmental characteristics of residential neighbourhoods, behavioural CM risk factors, and the metabolic syndrome (a combination of major biological cardio-metabolic risk factors), over a nine-year period.


Cardio-metabolic (CM) diseases are one of the leading causes of premature death worldwide and a major contributor to health disparities. Epidemiology has traditionally focused on individual-level risk factors of CM diseases, such as physical inactivity, unhealthy diet, obesity, hypertension, type 2 diabetes, and dyslipidemia. Environmental causes, however, remain poorly understood at the population level, and are therefore not addressed by public health interventions. Though some host-related factors do play a role, the dramatic increase in CM diseases over recent decades is largely attributed to changes in the socio-economic environment in which behavioural patterns occur, and in the physical environment, such as urban sprawl, amenities, transport infrastructure, which have resulted in socially patterned increases of motorized transportation, fast-food consumption, sedentary occupations and leisure activities, exacerbating CM-related disorders.


For this project, data from the ORISCAV-LUX study is employed. ORISCAV-LUX is a nationwide large scale population-based survey to monitor cardio-metabolic-cognitive and physical health of the resident population in Luxembourg.