Research activities

Funding – PhD training programmes

NextImmune logoNextImmune, an interdisciplinary PhD training programme supported by the PRIDE funding scheme, stands for “Next Generation Immunoscience: Advanced Concepts for Deciphering Acute and Chronic Inflammation”.  Inflammation is a protective response of the immune system to extreme challenges to homeostasis, such as infection, tissue stress and injury. The vulnerability to inflammation as well as its severity, its chronicity and its resolution can be influenced by genetic, epigenetic and environmental factors. A break of tolerance results in a pathologic immune response to otherwise harmless structures like autoantigens or allergens, triggered by innate inflammatory stimuli, such as infection, stress, molecular properties of the eliciting antigen or injury. NextImmune aims to bridge classical immunology and big-data analysis science in one doctoral training and education environment.

 

undefinedMICROH, meaning “Microbiomes in One Health”, is a competitive, interdisciplinary PhD training programme, supported by the PRIDE doctoral research funding scheme of the Luxembourg National Research Fund (FNR). MICROH aims to study interactions within and between microbiomes in relation to two major healthcare challenges of our time such as the increasing prevalence of chronic diseases. MICROH bridges microbiology and big data analytics in a structured doctoral training environment. By tackling frontier research questions of immediate public health relevance, the research-intensive programme responds to the unmet need of training the next generation of microbiome scientists in an interdisciplinary environment covering integration and analysis of multi-omics data, as well as basic and translational biomedical knowledge, and its practical application to the diagnosis of diseases and ultimately their treatment.

 

undefinedi2TRON, the most recently FNR-funded interdisciplinary PhD training programme, is entitled “Integrating immune strategies for Translational Research in Oncology and Neurology”. Inflammation represents a common hallmark shared across different non-communicable diseases (NCD) such as auto-immune disease, cancer and neurodegeneration. In Luxembourg, a considerable translational research expertise has been built up based on aberrant immune mechanisms bridging between these disease domains. i2TRON will leverage on this fundamental and clinical research expertise to train next generation translational scientists with the aim to advance our mechanistic insight on selected prototypic NCDs. Such insights will lead to discoveries of new biomarkers and therapeutic targets of NCDs, and facilitate translation into novel treatment strategies.

 

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