Activities

The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and a therapeutic approach to personalize health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.

Ongoing research projects address two major areas

Biomarkers

Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.

Therapeutics

By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.

The group also coordinates the EU-CardioRNA and Cardiolinc™ networks, which are a consortium of research groups aimed at advancing research on deciphering the role of RNAs in cardiovascular disease.

Strategic goals

• Address the main causes of mortality and morbidity in developed countries: heart and brain diseases

• Fulfil unmet medical needs: lack of diagnostic tools and drugs for personalized healthcare

• Develop networks of international collaborators

• Collaborate with private partners to bring research products to clinical application

• Perform translational research to push forward personalized medicine.

Brain heart Interaction