The Cardiovascular research unit aims to a better knowledge of the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approach to personalize healthcare. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
By addressing the mechanisms of the regulation of disease development by RNAs, the group aims to facilitate drug discovery.
The group also coordinates the EU-CardioRNA and Cardiolinc™ networks, which are consortium of research groups aiming to advance in the research deciphering the role of RNAs in cardiovascular disease.
• Address the main causes of mortality and morbidity in developed countries: heart and brain diseases
• Fulfil unmet medical needs: lack of diagnostic tools and drugs for personalized healthcare
• Develop networks of international collaborators
• Collaborate with private partners to bring research products to clinical application
• Perform translational research to push forward personalized medicine.